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Adenosine receptor A1 (A1)

Target Class
GPCR
Family
Adenosine
Official Symbol
ADORA1
Species
Human
Accession Number
AY136746
Alias Names
RDC7; adenosine A1 receptor; adenosine receptor A1
Background
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Adenosine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesCell Line
cAMPCHO-K1Human95-0061C2
β-ArrestinCHO-K1Human93-0787C2
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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