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Adenosine receptor A1 (A1)

Target Class
GPCR
Family
Adenosine
Official Symbol
ADORA1
Species
Human
Accession Number
AY136746
Alias Names
RDC7; adenosine A1 receptor; adenosine receptor A1
Background
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Adenosine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0787C2
cAMP CHO-K1 Human 95-0061C2
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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