Adenylate cyclase activating polypeptide receptor 1 (PAC1)
- Target Class
- GPCR
- Family
- VIP and PACAP
- Official Symbol
- ADCYAP1R1
- Species
- Human
- Accession Number
- AY366498
- Alias Names
- PAC1; PAC1R; PACAP receptor 1; PACAP type I receptor; PACAP-R1; PACAPR; PACAPRI; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; pituitary adenylate cyclase-activating polypeptide type I receptor
- Background
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
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Solution Portfolio
Related Family Members:
VIP and PACAP
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| Internalization |
U2OS |
Human |
93-0885C3 |
| β-Arrestin |
CHO-K1 |
Human |
93-0249C2 |
| cAMP |
CHO-K1 |
Human |
95-0064C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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