System ▲ | Relevance | Cell Type | Biomarker Readout |
StroHT29 | Host Stromal-Tumor Microenvironment, Oncology, Oncology - CRC | HT-29 colon adenocarcinoma cell line + Peripheral blood mononuclear cells + Primary human fibroblasts | CD106/VCAM-1, CD87/uPAR, CEACAM5/CD66e, Collagen I, Collagen III, CXCL10/IP-10, Keratin 20, MMP-9, PAI-I, PBMC Cytotoxicity, sGranzyme B, sIFN-γ, sIL-10, sIL-17A, sIL-2, sIL-6, SRB, sTNF-α, sVEGF, TIMP-2, tPA, uPA |
VascHT29 | Host Vascular-Tumor Microenvironment, Oncology, Oncology - CRC | HT-29 colon adenocarcinoma cell line + Peripheral blood mononuclear cells + Primary human endothelial cells | CCL2/MCP-1, CD106/VCAM-1, CD40, CD69, CD87/uPAR, CEACAM5/CD66e, Collagen IV, CXCL10/IP-10, CXCL9/MIG, Keratin 20, PBMC Cytotoxicity, sGranzyme B, sIFN-γ, sIL-10, sIL-17A, sIL-2, sIL-6, SRB, sTNF-α |