my cart
  • log-in
  • applications / products

    Applications

    • Drug Discovery & Development
    • Cell Banks for Bioassays
    • Potency & QC Lot Release
    • Detect Neutralizing Abs
    • Cytotoxicity Assays
    • Target Engagement
    • Translocation Assays
    • Targeted Protein Degradation
    • Signaling Pathway Reporters
    • Pharmacotrafficking Assays
    • Do-It-Yourself Assays
    • Therapeutic/Disease Area
    • Custom Development Capabilities

    Products

    • Cells & Cell Lines
    • Assay Ready Kits
    • Bioassay Kits
    • eXpress Kits
    • Frozen Cells
    • Membrane Preps
    • Proteins & Kinases
    • Cell Culture Reagents
    • Detection Reagents
    • Biochemical Assays
    • Control Ligands & Inhibitors
  • targets
    • A-Z List of Target List
    • GPCRs
    • Kinases
    • Checkpoint Receptors
    • Ion Channels
    • Cytokines & Interleukins
    • Signaling Pathways
    • Nuclear Proteins
    • Epigenetics Proteins
  • technologies / platforms
    • Enzyme Fragment Complementation
    • Human Primary Cell Screening
    • Competition Binding Platform
  • tools / resources

    Document Resource Library

    • Flyers & Brochure
    • User Manuals & Protocols
    • White Papers & Applications
    • Scientific Posters
    • Presentations

    Webinars

    Knowledge-Based Videos

    Blogs

    Scientific FAQs

    Publications & References

    CRO/CDMO Certification

    Reagent Calculators

    Instrument Compatibility

  • services
  • Contact Us
    • Customer & Technical Support
    • Submit an Order
    • Technical Resources
    • Literature & Email Signup
    • Legal & Policies
    • Locations
    • Distributors
    • Procurement Partners
  • about us
    • Company
    • Contact Us
    • Careers
    • Announcements
    • Events
Search Product
Contact a Specialist
mechanistic target of rapamycin (serine/threonine kinase) (MTOR)
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressiv...
/target-data-sheets/kinase/mtor 2/12/2015 9:47:37 PM
mTOR (1362-end), active

/products/proteins/14-770
mTOR (1362-end), active

/products/proteins/14-770m
unc-51-like kinase 1 (ULK1)
Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3- kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as ...
/target-data-sheets/kinase/ulk1 2/12/2015 9:48:35 PM
Application of a phenotypic drug discovery strategy to identify biological and chemical starting points for inhibition of TSLP production in lung epithelial cells.
Thymic stromal lymphopoietin (TSLP) is a cytokine released by human lung epithelium in response to external insult. Considered as a master switch in T helper 2 lymphocyte (Th2) mediated responses, TSLP is believed to play a key role in allergic diseases including asthma. The ...
/tools-resources/publications-references/publications/phenotypic-strategy-inhibit-tslp-lung-epitheli-(1) 1/24/2020 10:29:02 AM
ULK2, active

/products/proteins/14-772
ULK2, active

/products/proteins/14-772m
Wortmannin

/products/reagent/wortmannin-92-1095
Predicting Toxic and Therapeutic Mechanisms of the ToxCast Chemical Library by Phenotypic Screening
Addressing safety aspects of drugs and environmental chemicals relies extensively on animal testing.   However the quantity of chemicals needing assessment and challenges of species extrapolation  require development of alternative approaches. Using 8 primary human cell ...
/tools-resources/document-resource-library/documents/predictive-models-for-mechanism-of-action-clas-(1) 4/1/2014 10:14:48 PM
Gene Symbol
KINOME scan Gene Symbol td:first-child { background-color:#FFFFCC; } KINOMEscan Gene Symbol Entrez Gene Symbol Accession Number AAK1 AAK1 NP_055726.3 ABL1(E255K)-phosphorylated ABL1 NP_005148.2 ABL1(F317I)...
/services/drug-discovery-development-services/kinase-profiling/kinomescan/gene-symbol 3/4/2016 8:11:57 PM
|<  <   1 2    >  >| Pages: 1 of 2
+ sitemap © 2023 Eurofins DiscoverX Products. All rights reserved.
  • Contact Us
  • Legal & Privacy
  • Cookie Notice