/products/reagent/wnt-3a-protein-92-1100
/products/proteins/epi029
/products/cell-line/u2os-c3ar1-β-arrestin-cell-line-93-0814c3
/products/cell-line/cho-k1-c3ar1-gi-cell-line-95-0155c2
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
/target-data-sheets/gpcr/c3ar1
2/12/2015 9:43:26 PM
/products/cell-line/c3ar1-activated-gpcr-internalization-u2o-93-0771c3
We report the structure-activity relationships, design, and synthesis of the novel cannabinoid type 1 (CB1) receptor antagonist 3a (CP-945,598). Compound 3a showed subnanomolar potency at human CB1 receptors in binding (Ki = 0.7 nM) and functional assays (Ki = 0.12 nM). In viv...
/tools-resources/publications-references/publications/discovery-of-1-9-(4-chlorophenyl)-8-(2-chloropheny
10/3/2012 5:51:18 PM
Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicule. Target gene of Wnt signaling.
/target-data-sheets/gpcr/lgr5
2/12/2015 9:44:47 PM
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission me...
/target-data-sheets/kinase/csnk1g3
2/12/2015 9:46:36 PM
Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle prog...
/target-data-sheets/kinase/csnk2a2
2/12/2015 9:46:37 PM
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