Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phos...
/target-data-sheets/pathways/torc1
2/12/2015 9:45:56 PM
/products/cell-line/u2os-torc1-nuclear-translocation-cell-li-93-0833c3
/products/assay/torc1-nuclear-translocation-assay-93-0833e3cp19m
/products/assay/torc1-nuclear-translocation-assay-93-0833e3cp19l
/products/proteins/15-011
/products/proteins/15-011m
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, TORC1/CRTC1 and TORC2/CRTC2. Acts as a ...
/target-data-sheets/kinase/sik
2/12/2015 9:48:20 PM
Targets Assay Principles Contact a Specialist View by Signaling Pathway Signaling Pathway Product Solutions Interrogate a Variety of Popular Target-Specific Pathways with Cell-Based Assays Cellular pathway signaling constitutes key mechanisms by which biological in...
/targets/signaling-pathways
8/15/2012 5:56:46 PM