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TGR5 Receptor Agonist

/products/reagent/tgr5-receptor-agonist-92-1196
cAMP Hunter™ eXpress GPBAR1 CHO-K1 GPCR Assay

/products/assay/gpbar1-cho-k1-gpcr-assay-95-0049e2cp2m
cAMP Hunter™ eXpress GPBAR1 CHO-K1 GPCR Assay

/products/assay/gpbar1-cho-k1-gpcr-assay-95-0049e2cp2l
PathHunter® U2OS GPBAR1 β-Arrestin Cell Line

/products/cell-line/u2os-gpbar1-β-arrestin-cell-line-93-0794c3
cAMP Hunter™ CHO-K1 GPBAR1 Gs Cell Line

/products/cell-line/cho-k1-gpbar1-gs-cell-line-95-0049c2
cAMP Hunter™ CHO-K1 GPBAR1 Bioassay Kit

/products/assay/cho-k1-gpbar1-bioassay-kit-95-0049y2-00140
cAMP Hunter™ CHO-K1 GPBAR1 Bioassay Kit

/products/assay/cho-k1-gpbar1-bioassay-kit-95-0049y2-00139
Bile acid-induced TGR5-dependent c-Jun-N terminal kinase activation leads to enhanced caspase 8 activation in hepatocytes.
TGR5 is a novel G protein-coupled cell-surface bile acid receptor. In cholestasis, bile acids induce hepatocyte apoptosis by primarily activating death receptor-mediated signaling. We examined if bile acid-induced TGR5 activation is participating in bile acid-induced hepatocyt...
/tools-resources/publications-references/publications/bile-acid-induced-tgr5-dependent-c-jun-n-terminal 10/3/2012 5:51:11 PM
G protein-coupled bile acid receptor 1 (GPBA)
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase si...
/target-data-sheets/gpcr/gpbar1 2/12/2015 9:44:10 PM
PathHunter® Jurkat SIRPa Signaling Bioassay Kit

/products/assay/jurkat-sirpa-signaling-bioassay-k-93-1135y19-00129
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