TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM, Mar 2008]
/target-data-sheets/gpcr/taar1
2/12/2015 9:45:52 PM
/products/cell-line/cho-k1-taar1-gs-cell-line-95-0173c2
The hemagglutinin-tagged human trace amine-associated receptor1 (TAAR1) was stably coexpressed with rat Galpha(s) in the AV12-664 cell line, and receptor activation was measured as the stimulation of cAMP formation. After blockade of endogenously expressed alpha2- and beta-adr...
/tools-resources/publications-references/publications/pharmacologic-characterization-of-the-cloned-human
10/3/2012 5:51:09 PM
Amiodarone (Cordarone, Wyeth-Ayerst Pharmaceuticals) is a clinically available drug used to treat a wide variety of cardiac arrhythmias. We report here the synthesis and characterization of a panel of potential amiodarone metabolites that have significant structural similarity...
/tools-resources/publications-references/publications/trace-amine-associated-receptor-1-(taar1)-is-activ
10/3/2012 5:51:12 PM