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trace amine associated receptor 1 (TA1)
TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM, Mar 2008]
/target-data-sheets/gpcr/taar1 2/12/2015 9:45:52 PM
cAMP Hunterâ„¢ CHO-K1 TAAR1 Gs Cell Line

/products/cell-line/cho-k1-taar1-gs-cell-line-95-0173c2
Pharmacologic characterization of the cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1.
The hemagglutinin-tagged human trace amine-associated receptor1 (TAAR1) was stably coexpressed with rat Galpha(s) in the AV12-664 cell line, and receptor activation was measured as the stimulation of cAMP formation. After blockade of endogenously expressed alpha2- and beta-adr...
/tools-resources/publications-references/publications/pharmacologic-characterization-of-the-cloned-human 10/3/2012 5:51:09 PM
Trace amine-associated receptor 1 (TAAR1) is activated by amiodarone metabolites.
Amiodarone (Cordarone, Wyeth-Ayerst Pharmaceuticals) is a clinically available drug used to treat a wide variety of cardiac arrhythmias. We report here the synthesis and characterization of a panel of potential amiodarone metabolites that have significant structural similarity...
/tools-resources/publications-references/publications/trace-amine-associated-receptor-1-(taar1)-is-activ 10/3/2012 5:51:12 PM
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