Targets Assay Principles Product Highlights View Epigenetic Targets Epigenetic Proteins Product Highlights Biologically Relevant - Obtain quantitative cellular compound entry and epigenetic target binding data for more confident drug discovery decisions Easy-to-Use & Sc...
8/14/2012 9:56:32 PM
Rationale: Tyrosine kinase inhibitors used for oncology indications are associated with cardiovascular toxicity and patients taking the allosteric MEK inhibitor, trametinib, develop evidence of cardiomyopathy. We find that trametinib is active across a panel of human primary...
3/13/2017 9:47:37 PM