/products/membrane-preps/hts176m
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulat...
/target-data-sheets/gpcr/edg1
2/12/2015 9:43:47 PM
/products/frozen-cells/hts176rta
/products/cell-line/stable-cell-line/hts176c
The sphingolipid S1P (sphingosine 1-phosphate) is known to be involved in a number of pathophysiological conditions such as cancer, autoimmune diseases and fibrosis. It acts extracellularly through a set of five G-protein-coupled receptors, but its intracellular actions are...
/tools-resources/publications-references/publications/identification-and-characterization-of-a-mirror-im
9/14/2015 5:10:23 PM
We present the systematic prospective evaluation of a protein-based and a ligand-based virtual screening platform against a set of three G-protein-coupled receptors (GPCRs): the β-2 adrenoreceptor (ADRB2), the adenosine A(2A) receptor (AA2AR), and the sphingosine 1-phosphat...
/tools-resources/publications-references/publications/a-prospective-cross-screening-study-on-g-protein-c
9/14/2015 9:48:16 PM