The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby a...
/target-data-sheets/kinase/tbk1
2/12/2015 9:48:27 PM
/products/assay/adalimumab-bioassay-kit-93-0538b15-00132
/products/assay/adalimumab-bioassay-kit-93-0538b15-00131
/target-data-sheets/pathways/rank-iκb
2/12/2015 9:45:38 PM
PathHunter eXpress Pathway assay kits provide a robust, highly sensitive and easy-to-use method cell-based functional assay for IκB degradation and NFκB pathway activation. The eXpress kits contain everything needed for a complete IκB degradation assay including cells, detect...
/tools-resources/document-resource-library/documents/user-manual-pathhunter-express-degradation-assay
5/10/2016 4:51:36 PM
/products/cell-line/jurkat-iκb-degradation-cell-line-93-1121c19
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP >> PYY >= NPY.
/target-data-sheets/gpcr/mppyr1
2/12/2015 9:45:09 PM
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid.
/target-data-sheets/gpcr/ppyr1
2/12/2015 9:45:31 PM
/products/assay/cho-k1-c5ar1-bioassay-kit-93-0557y2-00060
/products/assay/cho-k1-c5ar1-bioassay-kit-93-0557y2-00059
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