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Programmed cell death 1 ligand 2 (PDL2)
Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene.PDCD1LG2 has also been designated as CD273 and has been speculated to play a major role in suppressing the immune system, with possible roles in cancer-in...
/target-data-sheets/checkpoint/pd-l2 12/4/2015 11:45:56 PM
PathHunter® U2OS PD-L2 Ligand Cell Line

/products/cell-line/u2os-pd-l2-ligand-cell-line-93-1076c3
KILR® U2OS PD-L2 Cell Line

/products/cell-line/u2os-pd-l2-cell-line-97-1036c003
Checkpoint Receptors
Applications Assay Principle Assay Highlights Advantages of Checkpoint Assays PathHunter checkpoint assays are MOA-reflective assays for quantifying a functional response as a result of direct ligand binding to its checkpoint receptor.  These cell-based assays enable rapid s...
/targets/checkpoint-assays 4/29/2020 4:06:29 PM
PathHunter® Jurkat PD-1 (SHP2) Signaling Cell Line

/products/cell-line/jurkat-pd-1-(shp2)-signaling-cell-line-93-1106c19
PathHunter® Jurkat PD-1 (SHP1) Signaling Cell Line

/products/cell-line/jurkat-pd-1-(shp1)-signaling-cell-line-93-1104c19
[2016 SLAS Conference Poster] Improved Cell-Based Assays To Assess Therapeutic Molecules Against Immune Checkpoint Receptors Such As PD-1, PD-L1 and PD-L2
Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many cancers. Therefore, therapeutics that block inhibitory receptors have proved to be powerful agents to restore anti-tumor i...
/tools-resources/document-resource-library/documents/2016-slas-conference-poster-improved-cell-based-as 1/6/2016 5:19:19 PM
Improved Cell-Based Assays To Assess Therapeutic Molecules Against Immune Checkpoint Receptors Such As PD-1, PD-L1 And PD-L2
Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many cancers. Therefore, therapeutics that block inhibitory receptors have proved to be powerful agents to restore anti-tumor imm...
/tools-resources/document-resource-library/documents/improved-cell-based-assays-to-assess-therapeutic-m 3/29/2016 10:33:14 PM
[PEGS 2017] Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many cancers. Therefore, therapeutics that block inhibitory receptors or activate immunostimulatory checkpoint receptors have pr...
/tools-resources/document-resource-library/documents/pegs-2017-novel,-improved-cell-based-assays-to-enable-immunotherapy-drug-development-for-checkpoin 4/28/2017 9:04:39 PM
[2016 PEGS Conference] Novel, Improved Cell-based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors
Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many cancers. Therefore, therapeutics that block inhibitory receptors or activate immunostimulatory checkpoint receptors have pro...
/tools-resources/document-resource-library/documents/2016-pegs-conference-novel-improved-cell-based-ass 4/14/2016 9:41:47 PM
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