/products/cell-line/u2os-pd-1-pd-1-dimerization-cell-line-93-1130c3
PD-1, functioning as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechani...
/target-data-sheets/checkpoint/pd-1
12/8/2015 11:24:30 PM
For Chemiluminescent Detection of PD-L1-Induced PD-1 Signaling
/tools-resources/document-resource-library/documents/user-manual-pathhunter-pd-1-signaling-bioassay-kit
11/7/2017 8:32:45 PM
/products/cell-line/jurkat-pd-1-(shp2)-signaling-cell-line-93-1106c19
/products/cell-line/jurkat-pd-1-(shp1)-signaling-cell-line-93-1104c19
/products/cell-line/jurkat-pd-1-nfat-signaling-pathway-repo-93-1153c19
An Application Note on automating Eurofins DiscoverX Cell-Based PathHunter® PD-1 Signaling Bioassay to bring high-throughput efficiencies to assay workflows. The need to improve efficiency in cell-based potency assays for high-throughput drug discovery workflows calls...
/tools-resources/document-resource-library/documents/automating-cell-based-bioassay-on-tecans-fluent
9/14/2022 5:38:37 PM
/products/cell-line/jurkat-pd-1-cell-line-97-1037c019
Reporter genes are a well-established method used to develop cell-based assays for testing drugs that inhibit targets involved in specific signaling pathways. Here, we introduce new PathHunter® Signaling Pathway Reporter Assays that utilize the industry-validated Enzyme Fra...
/tools-resources/document-resource-library/documents/dot-2020-signaling-pathways-poster
9/14/2020 8:59:34 PM
Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene.PDCD1LG2 has also been designated as CD273 and has been speculated to play a major role in suppressing the immune system, with possible roles in cancer-in...
/target-data-sheets/checkpoint/pd-l2
12/4/2015 11:45:56 PM
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