/target-data-sheets/checkpoint/ox40
2/5/2016 5:09:05 AM
/products/cell-line/u2os-ox40-signaling-cell-line-93-1080c3
/products/reagent/recombinant-human-ox40l-92-1312
Applications Assay Principle Assay Highlights Advantages of Checkpoint Assays PathHunter checkpoint assays are MOA-reflective assays for quantifying a functional response as a result of direct ligand binding to its checkpoint receptor. These cell-based assays enable rapid s...
/targets/checkpoint-assays
4/29/2020 4:06:29 PM
The PathHunter Co-Stimulatory Checkpoint Assay is a simple, highly specific assay to enable discovery and development of small molecule and biologic drugs targeting the TNFR family of receptors that activate the non-canonical NF-kB pathway through NF-kB inducing kinase (NIK)....
/tools-resources/document-resource-library/documents/user-manual-pathhunter-co-stimulatory-checkpoint-a
5/19/2016 8:52:52 PM
The PathHunter Checkpoint Signaling Assay for Tumor Necrosis Factor Receptor Superfamily (TNFRSF) members (or receptors) is a simple, highly specific assay to enable discovery and development of small molecule and biologic drugs targeting the TNFR superfamily of receptors that...
/tools-resources/document-resource-library/documents/user-manual-pathhunter®-checkpoint-receptor-tnfrsf
3/29/2018 6:15:49 PM
Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many cancers. Therefore, therapeutics that block inhibitory receptors or activate immuno-stimulatory checkpoint receptors have prove...
/tools-resources/document-resource-library/documents/dot-2017-novel,-improved-cell-based-assays-to-enable-immunotherapy-drug-development-for-checkpoint
9/22/2017 6:37:39 PM
Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many cancers. Therefore, therapeutics that block inhibitory receptors or activate immuno-stimulatory checkpoint receptors have prove...
/tools-resources/document-resource-library/documents/elrig-2017-novel,-improved-cell-based-assays-to-enable-immunotherapy-drug-development-for-checkpoi
9/26/2017 11:24:43 PM
Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many cancers. Therefore, therapeutics that block inhibitory receptors or activate immuno-stimulatory checkpoint receptors have prov...
/tools-resources/document-resource-library/documents/bebpa-2017-checkpoint-receptor-poster
9/27/2017 5:50:09 PM
PathHunter ® Screening & Profiling Services Discover Next Generation Targeted Therapeutics with Cell-Based Functional Assays Choose the Best Molecules for Preclinical and Clinical Study Eurofins DiscoverX’s PathHunter Screening and Profiling Services offers greate...
/services/drug-discovery-development-services/pathhunter-cell-based-services
4/12/2017 5:42:47 PM
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