This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interfe...
2/12/2015 9:47:22 PM
Features & Benefits Quantitate compound binding affinity against any kinase assay. Inhibitor binding constants (Kd values) are calculated from duplicate 11-point dose-response curves. Measurements are made under optimized conditions that generate true thermodynamic Kd val...
8/28/2012 2:01:20 AM
Features & Benefits The largest commercial kinase panel available, scanMAX contains a set of 468 kinases covering AGC, CAMK, CMGC, CK1, STE, TK, TKL, lipid and atypical kinase families, plus important mutant forms. scan MAX is an ideal choice for all stages of drug discovery ...
8/25/2012 7:55:39 PM
Features & Benefits An economical approach to surveying the human kinome, scan EDGE includes 97 kinases distributed throughout the AGC, CAMK, CMGC, CK1, STE, TK, TKL, lipid, and atypical kinase families, plus important mutant forms. scan EDGE is an economical alternative to...
8/28/2012 12:19:33 AM
Features & Benefits scan TK is the largest commercial panel of tyrosine kinases that includes a set of 135 both receptor and non-receptor kinases, plus important mutant forms. scan TK provides a comprehensive understanding of compound binding within the tyrosine kinase famil...
8/28/2012 1:43:52 AM
Features & Benefits A flexible 'a la carte' approach for customized kinase profiling. Select from KINOME scan's collection of 468 kinase assays and build your own customized assay panel of any size comprising only of kinases relevant to your programs. A simple, fast and cos...
9/15/2012 4:00:28 AM
Features & Benefits Quantitate compound binding affinity against the entire panel of KINOME scan kinase assays. Inhibitor binding constants (Kd values) are calculated from duplicate 11-point dose-response curves (plus DMSO control). Measurements are made under optimized con...
8/28/2012 2:40:25 AM
KINOME scan is the leading provider of selectivity profiling services for kinase inhibitor drug discovery. Leveraging our panel of over 450 kinase assays and our kinase inhibitor drug discovery expertise, KINOME scan provides investigators the benefit of kinome-wide profi...
8/15/2012 6:23:32 PM
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