/products/reagent/(-)-jq1-92-1149
Applications Assay Principle Product Highlights Advantages of SPRINTer Protein Turnover Biosensor Assays Homogeneous — Simple, scalable, and homogeneous no-wash protocol amenable to high-throughput screening (HTS) formats for increased efficiency Robust & Highly Sensiti...
/products-applications/targeted-protein-degradation
7/22/2020 8:54:53 PM
Applications Measure and Rank Inhibitory Potency Against Your Intracellular Protein Target Analyze a variety of intracellular protein targets such as kinases, hydrolases, methyltransferases, and bromodomains. ABL1 Tyrosine Kinase InCELL Pulse Assay ABL1 tyrosine kinase ce...
/products-applications/target-engagement-assays
2/16/2023 6:13:07 PM
Th17 responses are critical to a variety of human autoimmune diseases, and therapeutic targeting with monoclonal antibodies against IL-17 and IL-23 has shown considerable promise. Here, we report data to support selective bromodomain blockade of the transcriptional coactivato...
/tools-resources/publications-references/publications/bromodomain-inhibitor-cbp30-suppresses-th17
4/9/2019 8:54:22 AM