The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby a...
/target-data-sheets/kinase/tbk1
2/12/2015 9:48:27 PM
/products/assay/adalimumab-bioassay-kit-93-0538b15-00132
/products/assay/adalimumab-bioassay-kit-93-0538b15-00131
PathHunter eXpress Pathway assay kits provide a robust, highly sensitive and easy-to-use method cell-based functional assay for IκB degradation and NFκB pathway activation. The eXpress kits contain everything needed for a complete IκB degradation assay including cells, detect...
/tools-resources/document-resource-library/documents/user-manual-pathhunter-express-degradation-assay
5/10/2016 4:51:36 PM
/products/cell-line/jurkat-iκb-degradation-cell-line-93-1121c19
/products/assay/cho-k1-c5ar1-bioassay-kit-93-0557y2-00060
/products/assay/cho-k1-c5ar1-bioassay-kit-93-0557y2-00059
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast...
/target-data-sheets/kinase/ikk-epsilon
2/12/2015 9:47:13 PM
/products/cell-line/hek-293-iκb-degradation-cell-line-93-0538c1
/products/cell-line/u2os-iκb-degradation-cell-line-93-0538c3
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