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Assay List Discover New Ligands or Anti-Receptor and Anti-Ligand Antibodies Current cell-based methodologies to characterize biologics targeting interleukins include proliferation or cytokine release assays which require the use of primary cells. These primary cells introdu...
/services/drug-discovery-development-services/interleukin-profiling
6/20/2016 5:40:52 PM
Applications Assay Principle Contact a Specialist Eurofins DiscoverX cytokine receptor assays are available as complete ready-to-use bioassay and eXpress kits and stable cell lines formats for receptor activation and dimerization assessment. Please contact custom assay de...
/products-applications/cell-based-assays-for-biologics/interleukin
5/20/2015 8:36:11 PM
PGD2, produced by mast cells, has been detected in high concentrations at sites of allergic inflammation. It can stimulate vascular and other inflammatory responses by interaction with D prostanoid receptor (DP) and chemoattractant receptor-like molecule expressed on Th2 cells...
/tools-resources/publications-references/publications/prostaglandin-d2-causes-preferential-induction-of
10/3/2012 5:51:07 PM
Ligand-induced receptor dimerization is the first functional step in receptor activation, representing the most proximal, functional read-out for receptor activation. For the majority of Receptor Tyrosine Kinases these are homomultimer events whereas for cytokine receptor and ...
/tools-resources/document-resource-library/documents/detection-of-cytokine-and-growth-factor-receptor-d
1/23/2014 9:30:15 PM