/products/reagent/recombinant-human-il-17f-92-1259
Improper regulation of B cell responses leads to excessive production of antibodies and contributes to the development of autoimmune disease. T helper 17 (Th17) cells also drive the development of autoimmune disease, but the role of B cells in shaping Th17 cell-mediated immun...
/tools-resources/publications-references/publications/il-17a-production-distinct-from-il-17f-human-cells
4/8/2019 3:43:47 PM
Cystic fibrosis (CF) patients have mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel that result in reduced membrane expression and function. CF patients have impaired lung function due to chronic airway inflammation driven by dysr...
/tools-resources/document-resource-library/documents/2016-slas-conference-poster-phenotypic-characteriz
1/18/2016 10:14:06 PM
Applications Assay Principle Contact a Specialist Eurofins DiscoverX cytokine receptor assays are available as complete ready-to-use bioassay and eXpress kits and stable cell lines formats for receptor activation and dimerization assessment. Please contact custom assay de...
/products-applications/cell-based-assays-for-biologics/interleukin
5/20/2015 8:36:11 PM
Background/Purpose Proinflammatory cytokines cause joint inflammation and destruction in rheumatoid arthritis (RA) as exemplified by the therapeutic success of inhibiting tumor necrosis factor alpha (TNFa) by adalimumab (ADA) and interleukin (IL)-6 receptor (IL-6R) by toci...
/tools-resources/document-resource-library/documents/primary-human-cell-biomap-profiling-of-methotrexat
11/21/2013 9:00:54 PM