Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
/target-data-sheets/gpcr/gpr35
2/12/2015 9:44:21 PM
/products/cell-line/gpr35-activated-gpcr-internalization-u2o-93-0968c3
Drugs targeting the orphan receptor GPR35 have potential therapeutic application in a number of disease areas, including inflammation, metabolic disorders, nociception, and cardiovascular disease. Currently available surrogate GPR35 agonists identified from pharmacologicall...
/tools-resources/publications-references/publications/high-throughput-identification-and-characterizatio
8/19/2015 5:31:19 PM
/products/reagent/zaprinast-92-1048
/products/assay/gpr35-activated-gpcr-internalization-93-0968e3cp5m
/products/assay/gpr35-activated-gpcr-internalization-93-0968e3cp5l
/products/cell-line/cho-k1-gpr35-β-arrestin-cell-line-93-0355c2
/products/cell-line/cho-k1-gpr35-β-arrestin-cell-line-93-0942c2
/products/assay/gpr35-cho-k1-β-arrestin-gpcr-assay-93-0942e2cp2m
/products/assay/gpr35-cho-k1-β-arrestin-gpcr-assay-93-0942e2cp2l
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