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G-protein coupled receptor 35 (GPR35)
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
/target-data-sheets/gpcr/gpr35 2/12/2015 9:44:21 PM
PathHunter® GPR35 Activated GPCR Internalization U2OS Cell Line

/products/cell-line/gpr35-activated-gpcr-internalization-u2o-93-0968c3
High-throughput identification and characterization of novel, species-selective GPR35 agonists.
Drugs targeting the orphan receptor GPR35 have potential therapeutic application in a number of disease areas, including inflammation, metabolic disorders, nociception, and cardiovascular disease. Currently available surrogate GPR35 agonists identified from pharmacologicall...
/tools-resources/publications-references/publications/high-throughput-identification-and-characterizatio 8/19/2015 5:31:19 PM
Zaprinast

/products/reagent/zaprinast-92-1048
PathHunter® eXpress GPR35 Activated GPCR Internalization Assay

/products/assay/gpr35-activated-gpcr-internalization-93-0968e3cp5m
PathHunter® eXpress GPR35 Activated GPCR Internalization Assay

/products/assay/gpr35-activated-gpcr-internalization-93-0968e3cp5l
PathHunter® CHO-K1 GPR35 β-Arrestin Cell Line

/products/cell-line/cho-k1-gpr35-β-arrestin-cell-line-93-0355c2
PathHunter® CHO-K1 GPR35 β-Arrestin Cell Line

/products/cell-line/cho-k1-gpr35-β-arrestin-cell-line-93-0942c2
PathHunter® eXpress GPR35 CHO-K1 β-Arrestin GPCR Assay

/products/assay/gpr35-cho-k1-β-arrestin-gpcr-assay-93-0942e2cp2m
PathHunter® eXpress GPR35 CHO-K1 β-Arrestin GPCR Assay

/products/assay/gpr35-cho-k1-β-arrestin-gpcr-assay-93-0942e2cp2l
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