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G-protein coupled receptor 183 (GPR183)

/target-data-sheets/gpcr/mebi2 2/12/2015 9:44:59 PM
G protein-coupled receptor 183 (GPR183)
This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected...
/target-data-sheets/gpcr/ebi2 2/12/2015 9:43:47 PM
7α,25-dihydroxycholesterol

/products/reagent/7α,25-dihydroxycholesterol-92-1186
Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183).
Oxysterols are oxygenated cholesterol derivates that are emerging as a physiologically important group of molecules. Although they regulate a range of cellular processes, only few oxysterol-binding effector proteins have been identified, and the knowledge of their binding m...
/tools-resources/publications-references/publications/molecular-characterization-of-oxysterol-binding-to 8/18/2015 3:43:55 PM
Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor.
Oxysterols have recently been identified as natural ligands for a G protein-coupled receptor called EBI2 (aka GPR183) ( Nature 2011 , 475 , 524 ; 519 ). EBI2 is highly expressed in immune cells ( J. Biol. Chem. 2006 , 281 , 13199 ), and its activation has been shown to be c...
/tools-resources/publications-references/publications/identification-and-characterization-of-small-molec 8/18/2015 3:32:11 PM
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