/target-data-sheets/gpcr/mebi2
2/12/2015 9:44:59 PM
This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected...
/target-data-sheets/gpcr/ebi2
2/12/2015 9:43:47 PM
/products/reagent/7α,25-dihydroxycholesterol-92-1186
Oxysterols are oxygenated cholesterol derivates that are emerging as a physiologically important group of molecules. Although they regulate a range of cellular processes, only few oxysterol-binding effector proteins have been identified, and the knowledge of their binding m...
/tools-resources/publications-references/publications/molecular-characterization-of-oxysterol-binding-to
8/18/2015 3:43:55 PM
Oxysterols have recently been identified as natural ligands for a G protein-coupled receptor called EBI2 (aka GPR183) ( Nature 2011 , 475 , 524 ; 519 ). EBI2 is highly expressed in immune cells ( J. Biol. Chem. 2006 , 281 , 13199 ), and its activation has been shown to be c...
/tools-resources/publications-references/publications/identification-and-characterization-of-small-molec
8/18/2015 3:32:11 PM