Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system.
/target-data-sheets/gpcr/gpr18
2/12/2015 9:44:18 PM
/products/assay/gpr18-cho-k1-β-arrestin-orphan-gpcr-93-0560e2acp1m
/products/assay/gpr18-cho-k1-β-arrestin-orphan-gpcr-93-0560e2acp1l
/products/cell-line/cho-k1-gpr18-β-arrestin-orphan-gpcr-cel-93-0560c2a
GPR18 and GPR55 are orphan G protein-coupled receptors (GPCRs) that interact with certain cannabinoid (CB) receptor ligands. In the present study bicyclic imidazole-4-one derivatives were discovered as new scaffolds for the development of antagonists for GPR18 and GPR55. In...
/tools-resources/publications-references/publications/bicyclic-imidazole-4-one-derivatives-a-new-class-o
8/19/2015 4:24:30 PM
The decapeptide GnRH is known for its central role in the regulation of the hypothalamo-pituitary-gonadal axis. In addition, it is also known to have local effects within peripheral tissues. The zinc metalloendopeptidase, EC 3.4.24.15 (EP24.15), can cleave GnRH at the Tyr(5...
/tools-resources/publications-references/publications/activation-of-gpr18-by-cannabinoid-compounds-a-tal
8/18/2015 4:56:13 PM
/target-data-sheets/gpcr/mebi2
2/12/2015 9:44:59 PM
Adrenomedullin is a potent vasodilator peptide that exerts major effects on cardiovascular function. This gene encodes a seven-transmembrane protein that belongs to the family 1 of G-protein coupled receptors. Studies of the rat counterpart suggest that the encoded protein may...
/target-data-sheets/gpcr/gpr182
2/12/2015 9:44:18 PM
Endogenous mechanisms that orchestrate resolution of acute inflammation are essential in host defense and the return to homeostasis. Resolvin (Rv)D2 is a potent immunoresolvent biosynthesized during active resolution that stereoselectively stimulates resolution of acute i...
/tools-resources/publications-references/publications/identification-of-resolvin-d2-receptor-mediating-r
10/8/2015 10:05:25 PM
This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected...
/target-data-sheets/gpcr/ebi2
2/12/2015 9:43:47 PM
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