Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (M...
/target-data-sheets/gpcr/gpr161
2/12/2015 9:44:16 PM
/products/cell-line/cho-k1-gpr161-β-arrestin-orphan-gpcr-cel-93-0705c2