This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
2/12/2015 9:45:03 PM
The cAMP Hunter Semaglutide Bioassay Kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay asseses ligand (e.g. Exendin-4) based on activation of GLP1R GPCR activity via detection of cAMP. Activation of GLP1R eit...
10/12/2022 12:47:41 PM
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-li...
2/12/2015 9:44:09 PM
Applications Target-Based Bioassays Assay Highlights Advantages of Bioassay Bioassays are ideal for determining drug potency and stability using a simple, mix-&-read protocol that reflects the drug’s clinical mechanism of action. These rapid cell-based assays bypass the need...
9/21/2017 8:11:42 PM
Biologics represents one of the fastest growing classes of biopharmaceutical molecules today. One of the major bottlenecks in the development of biologics is the lack of ready-to-use bioassays for potency, stability and lot release testing. Ideal bioassays need to ref...
5/9/2014 9:50:13 PM
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