Resolution of acute inflammation is an active process that involves the biosynthesis of specialized proresolving lipid mediators. Among them, resolvin D1 (RvD1) actions are mediated by two G protein-coupled receptors (GPCRs), ALX/FPR2 and GPR32, that also regulate specific ...
/tools-resources/publications-references/publications/resolvin-d1-receptor-stereoselectivity-and-regulat
2/28/2013 6:35:44 PM
/target-data-sheets/gpcr/mfpr2
2/12/2015 9:45:01 PM
/products/membrane-preps/hts056m
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger...
/target-data-sheets/gpcr/fprl1
2/12/2015 9:44:03 PM
In this study, we determined receptor preferences for compound 43, a nitrosylated pyrazolone derivative, and the eicosanoid lipoxin A(4) (LXA(4)), potent anti-inflammatory mediators in many experimental in vivo models. Their effects have been suggested to be mediated throug...
/tools-resources/publications-references/publications/what-formyl-peptide-receptors-if-any-are-triggered
10/3/2012 5:50:59 PM
/products/cell-line/stable-cell-line/hts056c
/products/frozen-cells/hts056rta
Endogenous mechanisms regulating the host response during inflammation resolution are critical in ensuring disposal of noxious stimuli and return to homeostasis. In this article, we engineered novel Annexin A1 (AnxA1)-based peptides, AnxA1(2-50), that displayed specific bin...
/tools-resources/publications-references/publications/proresolving-and-tissue-protective-actions-of-anne
9/11/2015 5:21:34 PM