The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progress...
/target-data-sheets/kinase/erk1
2/12/2015 9:46:55 PM
/products/proteins/14-439
/products/proteins/14-439m
/products/proteins/14-515
/products/proteins/14-515m
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phospho...
/target-data-sheets/kinase/raf1
2/12/2015 9:48:09 PM
This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eI...
/target-data-sheets/kinase/mknk1
2/12/2015 9:47:33 PM
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progress...
/target-data-sheets/kinase/erk1(q122l)
1/6/2016 9:12:30 AM
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifun...
/target-data-sheets/gpcr/mcmklr1
2/12/2015 9:44:55 PM
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifun...
/target-data-sheets/gpcr/cmklr1
2/12/2015 9:43:38 PM
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