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DYRK1B, active

/products/proteins/14-944
DYRK1B, active

/products/proteins/14-944m
DYRK1A, active

/products/proteins/14-951
DYRK1A, active

/products/proteins/14-951m
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (DYRK1B)
DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identif...
/target-data-sheets/kinase/dyrk1b 2/12/2015 9:46:42 PM
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A)
This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It ...
/target-data-sheets/kinase/dyrk1a 2/12/2015 9:46:42 PM
Gene Symbol
KINOME scan Gene Symbol td:first-child { background-color:#FFFFCC; } KINOMEscan Gene Symbol Entrez Gene Symbol Accession Number AAK1 AAK1 NP_055726.3 ABL1(E255K)-phosphorylated ABL1 NP_005148.2 ABL1(F317I)...
/services/drug-discovery-development-services/kinase-profiling/kinomescan/gene-symbol 3/4/2016 8:11:57 PM
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk).
Continued examination of substituted 6-arylquinazolin-4-amines as Clk4 inhibitors resulted in selective inhibitors of Clk1, Clk4, Dyrk1A and Dyrk1B. Several of the most potent inhibitors were validated as being highly selective within a comprehensive kinome scan. Published by...
/tools-resources/publications-references/publications/potent-and-selective-small-molecule-inhibitors-of 10/3/2012 5:51:29 PM
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