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ChemiScreen™ CXCR7 Chemokine Receptor Membrane Preparation

/products/membrane-preps/hts138m
Chemokine (C-X-C motif) receptor 7 (CXCR7)
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The pr...
/target-data-sheets/gpcr/cxcr7 2/12/2015 9:43:43 PM
PathHunter® CXCR7 Activated GPCR Internalization U2OS Cell Line

/products/cell-line/cxcr7-activated-gpcr-internalization-u2o-93-0738c3
PathHunter® eXpress CXCR7 Activated GPCR Internalization Assay

/products/assay/cxcr7-activated-gpcr-internalizatio-93-0738e3cp27m
PathHunter® eXpress CXCR7 Activated GPCR Internalization Assay

/products/assay/cxcr7-activated-gpcr-internalizatio-93-0738e3cp27l
PathHunter® eXpress CXCR7 CHO-K1 β-Arrestin GPCR Assay

/products/assay/cxcr7-cho-k1-β-arrestin-gpcr-assay-93-0248e2cp2m
PathHunter® eXpress CXCR7 CHO-K1 β-Arrestin GPCR Assay

/products/assay/cxcr7-cho-k1-β-arrestin-gpcr-assay-93-0248e2cp2l
Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands.
CXCR7 binds chemokines CXCL11 (I-TAC) and CXCL12 (SDF-1) but does not act as a classical chemoattractant receptor. Using CCX771, a novel small molecule with high affinity and selectivity for CXCR7, we found that, although CXCR7 is dispensable for "bare filter" in vitro chem...
/tools-resources/publications-references/publications/elucidation-of-cxcr7-mediated-signaling-events-and 10/3/2012 5:51:38 PM
PathHunter® CHO-K1 CXCR7 (CMKOR1) β-Arrestin Cell Line

/products/cell-line/cho-k1-cxcr7-(cmkor1)-β-arrestin-cell-li-93-0248c2
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