Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifun...
/target-data-sheets/gpcr/cmklr1
2/12/2015 9:43:38 PM
/products/cell-line/cmklr1-activated-gpcr-internalization-u2-93-0720c3
Therapies that target leukocyte trafficking pathways can reduce disease activity and improve clinical outcomes in multiple sclerosis (MS). Experimental autoimmune encephalomyelitis (EAE) is a widely studied animal model that shares many clinical and histological features wi...
/tools-resources/publications-references/publications/a-novel-cmklr1-small-molecule-antagonist-suppresse
8/14/2015 5:28:48 PM
/products/assay/cmklr1-activated-gpcr-internalizati-93-0720e3cp22m
/products/assay/cmklr1-activated-gpcr-internalizati-93-0720e3cp22l
/products/cell-line/cho-k1-cmklr1-β-arrestin-cell-line-93-0313c2
/products/assay/cmklr1-cho-k1-β-arrestin-gpcr-assay-93-0313e2cp0m
/products/assay/cmklr1-cho-k1-β-arrestin-gpcr-assay-93-0313e2cp0l
/products/cell-line/cho-k1-cmklr1-gi-cell-line-95-0080c2
/products/assay/cmklr1-cho-k1-gpcr-assay-95-0080e2cp2m
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