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CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat.
BACKGROUND AND PURPOSE: Calcitonin gene-related peptide (CGRP) receptor antagonists effectively abort migraine headache and inhibit neurogenic vasodilatation in humans as well as rat models. Monoclonal antibodies typically have long half-lives, and we investigated whether or n...
/tools-resources/publications-references/publications/cgrp-function-blocking-antibodies-inhibit-neurogen 10/3/2012 5:51:13 PM
Calcitonin receptor-like (Calcitonin receptor-like receptor)
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAM...
/target-data-sheets/gpcr/calcrl-ramp1 2/12/2015 9:43:27 PM
ChemiScreen™ CGRP1 Calcitonin Receptor-Like Receptor Stable Cell Line

/products/cell-line/stable-cell-line/hts172c
Ready-to-Assay™ CALCRL Calcitonin Receptor Frozen Cells

/products/frozen-cells/hts172rta
ChemiScreen™ CGRP1 Calcitonin Receptor Membrane Preparation

/products/membrane-preps/hts172m
Calcitonin receptor-like (Calcitonin receptor-like receptor)
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAM...
/target-data-sheets/gpcr/calcrl-ramp3 2/12/2015 9:43:28 PM
Calcitonin receptor (CT)
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAM...
/target-data-sheets/gpcr/calcr-ramp3 2/12/2015 9:43:29 PM
Calcitonin receptor-like (Calcitonin receptor-like receptor)
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAM...
/target-data-sheets/gpcr/calcrl-ramp2 2/12/2015 9:43:28 PM
Structure–activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation.
BACKGROUND AND PURPOSE: The N-terminus of calcitonin gene-related peptide (CGRP) is important for receptor activation, especially the disulphide-bonded ring (residues 1-7). However, the roles of individual amino acids within this region have not been examined and so t...
/tools-resources/publications-references/publications/structure–activity-relationships-of-the-n-terminus 8/7/2015 5:36:18 PM
PathHunter® CHO-K1 CALCRL-RAMP1 (CGRP1) β-Arrestin Cell Line

/products/cell-line/cho-k1-calcrl-ramp1-(cgrp1)-β-arrestin-c-93-0269c2
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