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ChemiScreen™ Rhesus Macaque CCR5 Chemokine Receptor Membrane Preparation

/products/membrane-preps/hts010m
ChemiScreen™ Rhesus Macaque CCR5 Chemokine Receptor Stable Cell Line

/products/cell-line/stable-cell-line/hts010c
Ready-to-Assay™ CCR5 Chemokine Receptor Frozen Cells

/products/frozen-cells/hts010rta
PathHunter® CCR5 Activated GPCR Internalization U2OS Cell Line

/products/cell-line/ccr5-activated-gpcr-internalization-u2os-93-0653c3
Chemokine (C-C motif) receptor 5 (CCR5)
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tro...
/target-data-sheets/gpcr/ccr5 2/12/2015 9:43:31 PM
Biased and constitutive signaling in the CC-chemokine receptor CCR5 by manipulating the interface between transmembrane helices 6 and 7.
The equilibrium state of CCR5 is manipulated here toward either activation or inactivation by introduction of single amino acid substitutions in the transmembrane domains (TMs) 6 and 7. Insertion of a steric hindrance mutation in the center of TM7 (G286F in position VII:09/...
/tools-resources/publications-references/publications/biased-and-constitutive-signaling-in-the-cc-chemok 8/13/2015 4:27:05 PM
PathHunter® CHO-K1 CCR5 β-Arrestin Cell Line

/products/cell-line/cho-k1-ccr5-β-arrestin-cell-line-93-0224c2
PathHunter® eXpress CCR5 CHO-K1 β-Arrestin GPCR Assay

/products/assay/ccr5-cho-k1-β-arrestin-gpcr-assay-93-0224e2cp0m
PathHunter® eXpress CCR5 CHO-K1 β-Arrestin GPCR Assay

/products/assay/ccr5-cho-k1-β-arrestin-gpcr-assay-93-0224e2cp0l
cAMP Hunter™ CHO-K1 CCR5 Gi Cell Line

/products/cell-line/cho-k1-ccr5-gi-cell-line-95-0068c2
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