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Ready-to-Assay™ CCR4 Chemokine Receptor Frozen Cells

/products/frozen-cells/hts009rta
Chemokine (C-C motif) receptor 4 (CCR4)
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various type...
/target-data-sheets/gpcr/ccr4 2/12/2015 9:43:31 PM
ChemiScreen™ CCR4 Receptor Stable Cell Line

/products/cell-line/stable-cell-line/hts009c
PathHunter® CCR4 Total GPCR Internalization U2OS Cell Line

/products/cell-line/ccr4-total-gpcr-internalization-u2os-cel-93-0845c3
PathHunter® CHO-K1 CCR4 β-Arrestin Cell Line

/products/cell-line/cho-k1-ccr4-β-arrestin-cell-line-93-0193c2
PathHunter® eXpress CCR4 CHO-K1 β-Arrestin GPCR Assay

/products/assay/ccr4-cho-k1-β-arrestin-gpcr-assay-93-0193e2cp0m
PathHunter® eXpress CCR4 CHO-K1 β-Arrestin GPCR Assay

/products/assay/ccr4-cho-k1-β-arrestin-gpcr-assay-93-0193e2cp0l
PathHunter® eXpress CCR4 Total GPCR Internalization Assay

/products/assay/ccr4-total-gpcr-internalization-ass-93-0845e3cp27m
PathHunter® eXpress CCR4 Total GPCR Internalization Assay

/products/assay/ccr4-total-gpcr-internalization-ass-93-0845e3cp27l
Engagement of two distinct binding domains on CCL17 Is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung.
CCL17 (TARC) function can be completely abolished by mAbs that block either one of two distinct sites required for CCR4 signaling. This chemokine is elevated in sera of asthma patients and is responsible for establishing inflammatory sites through CCR4-mediated recruitment ...
/tools-resources/publications-references/publications/engagement-of-two-distinct-binding-domains-on-ccl1 8/13/2015 4:15:18 PM
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