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ChemiScreen™ CCR1 Chemokine Receptor Membrane Preparation

/products/membrane-preps/hts005m
ChemiScreen™ CCR1 Chemokine Receptor Stable Cell Line

/products/cell-line/stable-cell-line/hts005c
Ready-to-Assay™ CCR1 Chemokine Receptor Frozen Cells

/products/frozen-cells/hts005rta
PathHunter® CCR1 Activated GPCR Internalization U2OS Cell Line

/products/cell-line/ccr1-activated-gpcr-internalization-u2os-93-0651c3
PathHunter® CHO-K1 CCR1 β-Arrestin Cell Line

/products/cell-line/cho-k1-ccr1-β-arrestin-cell-line-93-0254c2
Chemokine (C-C motif) receptor 1 (CCR1)
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation ...
/target-data-sheets/gpcr/ccr1 2/12/2015 9:43:30 PM
PathHunter® U2OS CCR1 β-Arrestin-1 Cell Line

/products/cell-line/u2os-ccr1-β-arrestin-1-cell-line-93-0254c3
Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, β-arrestin translocation andchemotaxis assays.
BACKGROUND AND PURPOSE: Investigators have suggested that the chemokine receptor CCR1 plays a role in multiple myeloma. Studies using antisense and neutralizing antibodies to CCR1 showed that down-regulation of the receptor altered disease progression in a mouse model...
/tools-resources/publications-references/publications/identifying-bias-in-ccr1-antagonists-using-radiola 8/13/2015 3:54:33 PM
cAMP Hunter™ CHO-K1 CCR1 Gi Cell Line

/products/cell-line/cho-k1-ccr1-gi-cell-line-95-0066c2
PathHunter® eXpress CCR1 Activated GPCR Internalization Assay

/products/assay/ccr1-activated-gpcr-internalization-93-0651e3cp5m
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