/products/reagent/recombinant-murine-ccl22-92-1016
/products/reagent/recombinant-human-ccl22-92-1006
The chemokines CCL17 (TARC) and CCL22 (MDC) function through the same receptor, CCR4, but have been proposed to differentially affect the immune response. To better understand the role of the individual ligands, a panel of rat anti-mouse CCL17 surrogate antibodies was gener...
/tools-resources/publications-references/publications/surrogate-antibodies-that-specifically-bind-and-ne
8/13/2015 4:08:56 PM
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol- calcium second messenger system. Could play a role in lipopolysaccharide (LPS)-induced endotoxic shock...
/target-data-sheets/gpcr/mccr4
2/12/2015 9:44:53 PM
CCL17 (TARC) function can be completely abolished by mAbs that block either one of two distinct sites required for CCR4 signaling. This chemokine is elevated in sera of asthma patients and is responsible for establishing inflammatory sites through CCR4-mediated recruitment ...
/tools-resources/publications-references/publications/engagement-of-two-distinct-binding-domains-on-ccl1
8/13/2015 4:15:18 PM
/products/assay/ccr4-cho-k1-β-arrestin-gpcr-assay-93-0193e2cp0m
/products/assay/ccr4-cho-k1-β-arrestin-gpcr-assay-93-0193e2cp0l
/products/assay/mccr4-cho-k1-β-arrestin-gpcr-assay-93-0515e2mcp0m
/products/assay/mccr4-cho-k1-β-arrestin-gpcr-assay-93-0515e2mcp0l
/products/cell-line/cho-k1-ccr4-β-arrestin-cell-line-93-0193c2
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