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Aldosterone

/products/reagent/aldosterone-92-1131
Nuclear receptor subfamily 3, group C, member 2 (Mineralcorticoid receptor) (NR3C2)
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transac...
/target-data-sheets/nhr/mr 2/12/2015 9:45:10 PM
Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison.
The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion is mediated by either Gq/11 proteins or βarrestin1 (βarr1), both of which can couple to its type 1 receptors (AT₁Rs), present in adrenocortical zona glomerulosa (AZG) cell membranes...
/tools-resources/publications-references/publications/suppression-of-adrenal-βarrestin1-dependent-aldost 8/7/2015 4:59:31 PM
Angiotensin II receptor, type 1 (AT1)
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 recept...
/target-data-sheets/gpcr/agtr1 2/12/2015 9:43:11 PM
5-Hydroxytryptamine receptor 2A (m5HT2A)
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium...
/target-data-sheets/gpcr/mhtr2a 2/12/2015 9:45:04 PM
PathHunter® eXpress CHO-K1 MR Protein Interaction Assay

/products/assay/cho-k1-mr-protein-interaction-assay-93-0758h2cp13s
PathHunter® eXpress CHO-K1 MR Protein Interaction Assay

/products/assay/cho-k1-mr-protein-interaction-assay-93-0758h2cp13m
Angiotensin II, Human

/products/reagent/angiotensin-ii-human-92-1077
QRFP-26/P518

/products/reagent/qrfp-26-p518-92-1194
PathHunter® CHO-K1 MR Protein Interaction Cell Line

/products/cell-line/cho-k1-mr-protein-interaction-cell-line-93-0758c2
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