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CCR9-mediated signaling through β-catenin and identification of a novel CCR9 antagonist.
Elevated levels of chemokine receptor CCR9 expression in solid tumors may contribute to poor patient prognosis. In this study, we characterized a novel CCR9-mediated pathway that promotes pancreatic cancer cell invasion and drug resistance, indicating that CCR9 may play a...
/tools-resources/publications-references/publications/ccr9-mediated-signaling-through-β-catenin-and-iden 9/21/2015 7:58:17 PM
Catenin (cadherin-associated protein), beta 1 (CTNNB1)
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the a...
/target-data-sheets/pathways/β-catenin 2/12/2015 9:46:03 PM
Discovery of novel small molecule activators of β-catenin signaling
Wnt/β-catenin signaling plays a major role in embryonic development and adult stem cell maintenance. Reduced activation of the Wnt/β-catenin pathway underlies neurodegenerative disorders and aberrations in bone formation. Screening of a small molecule compound library w...
/tools-resources/publications-references/publications/oral-ondansetron-for-gastroenteritis-in-a-pedi-(2) 3/8/2013 5:26:50 PM
b-catenin, activated

/products/proteins/23-027 4/17/2023 6:27:20 PM
b-catenin, activated

/products/proteins/23-027m 4/17/2023 6:27:20 PM
PathHunter® U2OS β-Catenin Nuclear Translocation Cell Line

/products/cell-line/u2os-β-catenin-nuclear-translocation-cel-93-0743c3
PathHunter® eXpress β-Catenin Nuclear Translocation Assay

/products/assay/β-catenin-nuclear-translocation-ass-93-0743e3cp22m
PathHunter® eXpress β-Catenin Nuclear Translocation Assay

/products/assay/β-catenin-nuclear-translocation-ass-93-0743e3cp22l
Recombinant Proteins
Contact a Specialist Products All proteins Kinases – View over 440 active, inactive, and unactivated kinases available as human, mouse, rat, and other species; expressed from bacterial, insect, or mammalian cells Phosphatases – Utilize the same phosphatase, expre...
/products-applications/recombinant-proteins 9/24/2019 1:24:47 PM
UbcH4, active

/products/proteins/23-025
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