Webinars

Showing 1–12 of 22 results

Webinars Functional Assays for the Development of Agonistic Abs for Immunotherapies

Webinars Implementing ADCC assays in QC: When donor variability isn’t an option

Inherent donor variability of immune effector cells presents a significant challenge for developing a robust and reproducible ADCC assays for…

Webinars Create Your Own InCELL Pulse Cellular Compound Target Engagement Assay

It is well established that ligand binding can protect proteins from thermal denaturation in a cellular milieu; however, the broad…

Webinars Create Your Own Cell-Based Assays to Study Receptor Tyrosine Kinase Function

Protein kinases are critical to many cellular pathways and play a role in several therapeutic areas such as oncology, inflammation,…

Webinars Duplexed Screening of GPCRs to Measure Calcium and β-Arrestin

The screening and functional characterization of novel ligands for G-Protein Coupled Receptors (GPCR) remains a key focus in drug discovery.…

Webinars How to Make Your Own Cell-Based Assays to Study β-Arrestin Recruitment

This 30-minute webinar shows you how to make your own cell-based assays to analyze β-arrestin recruitment in any cell type.…

Webinars Immuno-Oncology Drug Development Profiling Immunomodulatory Biologics and Compounds

The complex interactions between tumor cells and the host immune system are only beginning to be understood, however it is…

Webinars Creating Cellular Target Engagement Assays for Diverse Kinases Using InCELL Pulse

Kinase inhibitors often potently inhibit several off-target kinases in biochemical assays. Unfortunately, the relevance of these off-target interactions in a…

Webinars Mu Opioid Receptor Splicing and Signaling: Another Dimension of GPCR Function

Opioid receptors are among the most well-known GPCRs that regulate the transmission and perception of pain. Clinical management of severe…

Webinars Create Your Own Cellular Compound Target Engagement Assay

Here we will describe InCELL Pulse™, which uses DiscoverX’s Enzyme Fragment Complementation (EFC) technology to overcome these limitations of current…

Webinars Driving Robust ADCC and T Cell Redirection with KILR CD16 Effector Cells

PBMC effector cells have inherent donor variability, reducing their consistency and reproducibility in lot release assays. Antibody-Dependent Cell Cytotoxicity (ADCC)…

Webinars Application of β Arrestin Assays to the Orphan GPCR World

GPCRs are privileged drug targets. Approximately 100 receptors still escape from the drug discovery process as they are orphans, without…