Kinase Solutions
High-Quality, Cellular and Biochemical Kinase Assays with Full Human Kinome Coverage
DiscoverX offers accurate, reproducible kinase assays with complete human kinome coverage so you can always find a solution for your kinase target. Our
in vitro biochemical kinase panel,
KINOMEscan®,includes an industry-leading set of nearly 500 assays, allowing rapid and efficient determination of kinome-wide potency and selectivity of compounds. By integrating EFC technology with deep kinase knowledge and cell-based assays expertise, we offer a growing menu of cellular,
functional assays to detect activated kinases along with binding assays for
compound-target engagement. When used alone or in combination, these robust assay platforms can be used at all stages of drug discovery and are ideal for identifying highly potent and selective kinase inhibitors.
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Build Your Own Kinase Panel
scanELECT® Kinase Selectivity & Profiling Services
Select from KINOMEscan's collection of 468 kinase assays and build your own customized assay panel of any size containing kinases relevant to your program. scanELECT is a flexible solution to meet your screening needs of any library size or any stage in the drug discovery pipeline.
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Expedite Lead Optimization with Kinase Screening Services
KINOMEscan Kinase Profiling Services
The leading selectivity profiling service for kinase inhibitor drug discovery. Leveraging both our panel of over 480 kinase assays and our kinase inhibitor drug discovery expertise, KINOMEscan provides investigators the benefit of kinome-wide profiling, the flexibility to create personalized screening solutions, and the knowledge to support and inform decision making throughout the kinase drug development continuum.
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Robust, Cellular Functional Receptor Kinase Assays
PathHunter® Cell-Based Assays for RTKs and CTKs
Fully optimized, target-validated cell-based kinase assays allow you to study kinase activation, dimerization, receptor internalization, SH2-recruitment, and screen for novel kinase inhibitors of both receptor tyrosine kinase (RTK) and cytosolic tryosine kinase (CTK). Our growing panel of tyrosine kinase assays are available as cell lines, assay ready kits, build-your-own assay tools, or services.
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Universal Compound-Target Engagement Cell-Based Assays
InCELL Cell-Based Assays for Intracellular Kinases
InCELL Hunter™ and InCELL Pulse™ cellular compound-target engagement assays provide the ability to create your own assays for intracellular kinases as well as confirm compound cell entry, target binding, screen inhibitors, measure cellular EC50 values, and rank compounds--all in the native cellular environment
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Simple Fluorescent Assay for Kinase Profiling and Screening
ADP Accumulation Assay
The ADP Accumulation Assay is a generic, antibody-free, homogeneous assay platform that detects kinase activity by monitoring ATP depletion. Reliably measure phosphotransferase-mediated production of ADP, providing a positive signal that increases in direct proportion to ADP accumulation.
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Webinars
KINOME
scan Kinase Broad Profiling and Phenotypic Screening
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InCELL Cellular Compound Target Engagement
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Blog Articles
The Key to Designing a Kinase Screening Project
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Critical Needs in Cellular Target Engagement
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Kinome-Wide Profiling of Existing Chemical Assets: A Powerful Strategy to Jump-Start New Drug Discovery Programs
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DiscoverX and the SGC Partner to Make an Annotated Collection of >600 Kinase Inhibitors Freely Available
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Brochures and Flyers
KINOME
scan KdELECT
® Kinase Screening and Profiling
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InCELL Target Engagement Assays
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PathHunter Protein Translocation Assays
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PathHunter MAX Panel Screening and Profiling Services
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Resources
Kinase Targets
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Kinase Publications
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KINOME
scan Tools and Resources
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InCELL Pulse Target Engagement Kinase Reference Set
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Custom Assay Development Services
Can't find your assay on the menu? We can develop it for you.
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Technical Bulletins
Updated Cell Culture and Handling Procedure.
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