| Biological Information | |
|---|---|
| Background Information: | TTBK2 (Tau tubulin kinase 2) is a serine/threonine protein kinase that is involved in a variety of cellular processes, including regulation of the cytoskeleton, intracellular transport, and neuronal development and function. TTBK2 has been shown to be involved in the regulation of microtubule dynamics and stability, and alterations in TTBK2 expression and activity have been linked to neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Research has suggested that TTBK2 may also play a role in cancer. TTBK2 has been shown to be overexpressed in several types of cancer, including breast cancer and glioblastoma, and high levels of TTBK2 expression have been associated with poor prognosis. Additionally, TTBK2 has been suggested as a potential therapeutic target in cancer, and efforts to develop small-molecule inhibitors of the kinase are underway. |
| Target Class: | Kinase |
| Accession Number: | BC071556.1 |
| Target Name: | TTBK2 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
TTBK2, active
N-terminal GST-tagged, recombinant, human TTBK2 amino acids 1-331 expressed by baculovirus in Sf21 insect cells. Purified using glutathione agarose followed by size exclusion chromatography.
Datasheets
15-019x Datasheet
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