Biological Information

Background Information:

SUV39H2 (Suppressor of variegation 3-9 homolog 2) is a histone methyltransferase that plays a key role in the regulation of gene expression through the modification of chromatin structure. Specifically, SUV39H2 catalyzes the transfer of methyl groups to the lysine 9 residue of histone H3, leading to the formation of H3K9me3, a repressive chromatin mark that is associated with transcriptional silencing.
SUV39H2 is involved in the regulation of various cellular processes, including cell differentiation, DNA damage response, and maintenance of genomic stability. It also plays a role in X-chromosome inactivation in female mammals, where it is responsible for the establishment and maintenance of heterochromatin at the inactive X chromosome.
SUV39H2 is an important histone methyltransferase that plays a critical role in the regulation of gene expression and the maintenance of chromatin structure.

Target Class:

Epigenetic

Family:

Histone Methyltransferase (HMT)

Sub Family:

Writer

Protein Name:

SUV39H2

Accession Number:

NP_001180353.1

UniProt Number:

Q9H5I1

Gene Name:

SUV39H2

Gene ID:

79723

Gene Aliases:

FLJ23414|KMT1B

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic