| Biological Information | |
|---|---|
| Background Information: | SIK (Myocardial Snf1-Like Kinase or Msk) was initially identified as a Ser/Thr kinase with homology to yeast Snf1 that is involved in mouse cardiogenesis. The human gene maps to a chromosomal region associated with congenital heart defects in Down's syndrome. Snf1 is a histone kinase (H3, Ser10) that may be involved in transcriptional regulation; a role for SIK in histone modification has not yet been firmly established. SIK3 IS involved in positive regulation of TORC1 signaling, positive regulation of TORC2 signaling, and protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022] |
| Target Class: | Kinase |
| Accession Number: | BC128510.1 |
| Target Name: | SIK3 |
| Target Aliases: | SIK Family Kinase 3, QSK, Salt-Inducible Kinase 3, L19, Serine/Threonine-Protein Kinase SIK3 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
SIK3, active
N-terminal GST and C-terminal 6His-tagged, recombinant, human SIK3 amino acids 1-307.
Datasheets
15-011x Datasheet
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