Biological Information
Background Information:
SIK (Myocardial Snf1-Like Kinase or Msk) was initially identified as a Ser/Thr kinase with homology to yeast Snf1 that is involved in mouse cardiogenesis. The human gene maps to a chromosomal region associated with congenital heart defects in Down's syndrome. Snf1 is a histone kinase (H3, Ser10) that may be involved in transcriptional regulation; a role for SIK in histone modification has not yet been firmly established. SIK3 IS involved in positive regulation of TORC1 signaling, positive regulation of TORC2 signaling, and protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
Target Class:
Kinase
Family:
CAMK
Sub Family:
Protein Ser/Thr
Protein Name:
QSK (SIK3)
Accession Number:
BC128510.1
UniProt Number:
Q9Y2K2
Gene Name:
SIK3
Gene ID:
23387
Gene Aliases:
FLJ12240|L19|KIAA0999|QSK
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Bioassay Data
Trademark Statement:
For Research Use Only