Biological Information
Background Information:
SIK2 phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. It inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Target Class:
Kinase
Family:
CAMK
Sub Family:
Protein Ser/Thr
Protein Name:
SIK2
Protein Aliases:
Qin-induced kinase|Salt-inducible kinase 2|SIK-2|Serine/threonine-protein kinase SNF1-like kinase 2
Accession Number:
NM_015191.1
UniProt Number:
Q9H0K1
Gene Name:
SIK2
Gene ID:
23235
Gene Aliases:
KIAA0781|QIK|DKFZp434K1115|LOH11CR1I
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic