Rsk4, active

Background Information:

RSK4 (Ribosomal S6 kinase 4) is a serine/threonine protein kinase that belongs to the RSK (Ribosomal S6 kinase) family of kinases. It is involved in a variety of cellular processes, including cell growth and differentiation, transcriptional regulation, and cytoskeletal dynamics. Research has suggested that RSK4 plays a role in several diseases, including cancer and X-linked mental retardation. Mutations in the RSK4 gene have been linked to Coffin-Lowry syndrome, a rare genetic disorder characterized by intellectual disability, facial abnormalities, and other physical features. Additionally, RSK4 has been shown to be involved in the regulation of insulin signaling and glucose metabolism, making it a potential target for the treatment of type 2 diabetes.

Target Class:

Kinase

Family:

AGC

Sub Family:

Protein Ser/Thr

Protein Name:

RSK4

Protein Aliases:

90 kDa ribosomal protein S6 kinase 6|p90-RSK 6|p90RSK6|Ribosomal S6 kinase 4|RSK-4|pp90RSK4

Accession Number:

NM_014496.2

UniProt Number:

Q9UK32

Gene Name:

RPS6KA6

Gene ID:

27330

Gene Aliases:

RSK4

Target Species:

Human