| Biological Information | |
|---|---|
| Background Information: | Rse (TYRO3 protein tyrosine kinase), also known as Brt, BYK, Dtk, Etk3, Sky, Tif, or even sea-related receptor tyrosine kinase, is a receptor tyrosine kinase with homology to Axl. Rse is widely expressed in the adult and present in variable amounts in neural, lymphoid, vascular, and reproductive tissues. It plays a role in PI-3 kinase signaling and clearance of apoptotic cells. Gas6 acts directly on mature osteoclasts through activation of Tyro 3 and p42/p44 MAPK, possibly contributing to the bone loss by estrogen deficiency.
GenBank D17517 |
| Target Class: | Kinase |
| Accession Number: | NM_006293.2 |
| Target Name: | Rse |
| Target Aliases: | TYRO3, Brt, Sky, BYK, DTK, RSE, Tif, Dtk, SKY |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
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Rse, active
N-terminal 6His-tagged recombinant, human Rse, amino acids 451-end.
Datasheets
14-535x Datasheet
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