RIPK1, active

Background Information:

RIPK1 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]

Target Class:

Kinase

Family:

TKL

Sub Family:

Protein Ser/Thr

Protein Name:

RIPK1

Protein Aliases:

receptor-interacting protein kinase 1

Accession Number:

NM_003804.3

UniProt Number:

Q13546

Gene Name:

RIPK1

Gene ID:

8737

Gene Aliases:

RIP

Target Species:

Human