Biological Information
Background Information:
Platelet-derived growth factor BB (PDGF-BB) is a homodimeric protein that is released upon platelet activation that induces proliferation, migration, and survival of endothelial, epithelial, and smooth muscle cells, as well as fibroblasts. A potent mitogen for mesenchymal cells, PDGF-BB is able to bind PDGFRa and PDGFRb, and plays an important part in healing, regeneration, angiogenesis and formation of smooth muscle during embryonic development. May facilitate tumor metastasis and vascularization. Provided as 2μg of dry powder alongside reconstitution buffer.
Target Class:
Growth Factor
Target Species:
Human
Usage
Product Type:
Recombinant Proteins
Application:
Drug Discovery & Development
Storage Conditions:
Store at ≤-20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®