Biological Information
Background Information:
CCL3 is a small cytokine protein that acts as an agonist for CCR1 and CCR5. It plays a critical role in the recruitment of leukocytes to the site of inflammation. While both CCL3 and CCL4 attract monocytes, macrophages, and dendritic cells to the site of infection, CCL3 attracts CD8+ T cells, while CD4+ T cells are more responsive to CCL4. In addition to these functions, CCL3 also induces inflammatory cytokine secretion, mast cell degranulation, and NK cell activation. Provided as 5 μg of dry powder alongside reconstitution buffer.
Target Class:
Cytokine
Family:
Chemokine
Sub Family:
CC Chemokines
Target Species:
Human
Usage
Product Type:
Recombinant Proteins
Application:
Drug Discovery & Development
Storage Conditions:
Store at ≤-20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®