Biological Information
Background Information:
CCL22 is a small cytokine protein that induces the migration of CCR4+ Th2 cells, regulatory T cells, dendritic cells, and NK cells. CCL22 secretion is induced by LPS and CD40 antibody in macrophages, and is upregulated by Th2 cytokines (IL-4 and IL-5) and downregulated by Th1 cytokines (IFNγ). Carries out its functions primarily by interacting with its chemokine receptor, CCR4, as an agonist. Provided as 5 μg of dry powder alongside reconstitution buffer.
Target Class:
Cytokine
Family:
Chemokine
Sub Family:
CC Chemokines
Target Species:
Human
Usage
Product Type:
Recombinant Proteins
Application:
Drug Discovery & Development
Storage Conditions:
Store at ≤-20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®