Biological Information
Background Information:
CCL2 is a protein involved in chemoattraction which attracts monocytes, activated T cells, basophils, NK cells, and immature dendritic cells to the site of inflammation. CCL2 acts as an agonist on CCR receptors including CCR2, CCR3, and CCR5. Additionally, it is believed to reduce IL-12 production by dendritic cells and promote a Th2 phenotype in CD4+ T cells. Implicated in the pathology of multiple sclerosis, atherosclerosis, and allergic asthma. Provided as 5 μg of dry powder alongside reconstitution buffer.
Target Class:
Cytokine
Family:
Chemokine
Sub Family:
CC Chemokines
Target Species:
Human
Usage
Product Type:
Recombinant Proteins
Application:
Drug Discovery & Development
Storage Conditions:
Store at ≤-20°C. Please avoid multiple freeze/thaw cycles.
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Additional Information
Brand:
Eurofins DiscoverX®